Murphysboro High School announced on October 12, 2025, that it will host the 1A High School Regional, sharing game schedules and ticket information on its X account.
Murphysboro High School posted messages on October 7, 2025 thanking South Paw Bar and Grill as well as parent volunteers for their support of school activities.
Murphysboro High School published several posts between October 3 and October 4 highlighting school activities and announcing a volleyball victory over Johnston City.
In Williamson County school districts, 433 Hispanic students were enrolled in the 2023-24 school year, according to the Illinois State Board of Education.
In Williamson County school districts, 568 Black students were enrolled in the 2023-24 school year, according to the Illinois State Board of Education.
On September 20, 2025, Murphysboro High School publicly thanked Bradley Padgett from Walmart and Boy Scout Troop #4 for their contributions supporting the football team.
Murphysboro High School issued updates on September 18–19 regarding entry changes due to gym construction and highlighted a decisive win by its boys’ soccer team over Pinckneyville.
In Williamson County school districts, 119 Asian students were enrolled in the 2023-24 school year, according to the Illinois State Board of Education.